July 2026 What if stress makes us consume more without making us enjoy what we consume? In a triple-blind crossover experiment, 66 healthy adults with little previous opioid exposure underwent either social-evaluative stress—the pressure of being judged by others—or a neutral condition, then received oxycodone, a prescription opioid painkiller, or saline. They could subsequently work to obtain more of the sampled dose. Stress increased oxycodone self-administration by six per